Rare Autoimmune Diseases
Scleroderma
Scleroderma
is considered an autoimmune
rheumatic disease, refers to a range of disorders in which the skin
and connective tissues tighten and harden and a connective tissue disorder. It
is a long-term, progressive disease. Scleroderma is not contagious,
infectious, cancerous or malignant. Reason
behind this diseases is our immune system, which causes the body to make too
much of the protein collagen, in which the skin gets thick and tight, and scars
can form on lungs and kidneys. The blood vessels became thicken and not work
the way they should. This leads to tissue damage and high blood pressure.
Types of Scleroderma
1. Localised scleroderma (affects the skin)
2. Systemic sclerosis – (affect blood circulation
and internal organs as well as the skin)
v Localised
sclerodermas are of 2 types.
·
Morphea: Symptoms include oval-shaped
patches on the skin, the shapes have a purple border, and they are
white in the middle.
·
Linear scleroderma: This kind causes streaks
of hardened skin to form on the arms, legs, or face. It can affect bones and
muscles.
v Systemic
sclerosis are of 2 types
·
Limited cutaneous systemic sclerosis: It
affects the skin of the face, hands, and feet, and lower arms and legs. It can
also damage the lungs, intestines, or oesophagus. is the least severe type of
systemic scleroderma
·
Diffuse scleroderma: This involves skin
thickening which affects the area from the hands to above the wrists. It also
affects internal organs, like the heart, lungs, kidneys, and gastrointestinal
tract.
Currently, there is no cure for scleroderma, but
there are many treatments available to help particular symptoms, also no
medication can stop the overproduction of collagen. For instance, heartburn can
be controlled by medications called proton pump inhibitors PPIs) or medicine to
improve the motion of the bowel. Some treatments are directed at decreasing the
activity of the immune system.
Common treatments include:
·
Medication to improve circulation
·
Medicines that reduce the activity of
the immune system
·
Steroid medication to reduce muscle
problems
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